Bioactivity:

GNE-617 hydrochloride is a potent and competitive inhibitor of nicotinamide phosphoribosyltransferase (IC50: 5nM). GNE-617 hydrochloride reduces the NAD levels in a > 95% reduction in both NAPRT1-deficient and NAPRT1-proficient cell lines and exerts (EC50

CAS nr:

T22801

Purity:

98%

Molecular Weight:

463,88

SMILES:

FC1=CC(F)=CC(S(C2=CC=C(C/N=C(O)/C3=CN4C=CN=C4C=C3)C=C2)(=O)=O)=C1.Cl

Formula:

C21H16ClF2N3O3S

Pathway:

Others

Target:

Others