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Bioactivity:
MK-8353 is a potent, selective and orally available inhibitor of ERK1/2 (IC50s of 23.0 nM and 8.8 nM, respectively)
CAS nr:
1184173-73-6
Purity:
98%
Molecular Weight:
691,84
SMILES:
O=C([C@@]1(SC)CN(CC(N2CC=C(C3=CC=C(C4=NN(C)C=N4)C=C3)CC2)=O)CC1)NC5=CC6=C(NN=C6C7=CC=C(OC(C)C)N=C7)C=C5
Formula:
C37H41N9O3S
Pathway:
MAPK
Target:
ERK