Bioactivity:

Lumateperone Tosylate is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM).

CAS nr:

1187020-80-9

Purity:

98%

Molecular Weight:

565,7

SMILES:

CC1=CC=C(C=C1)S(O)(=O)=O.[H][C@]12CCN(CCCC(=O)C3=CC=C(F)C=C3)C[C@@]1([H])C1=C3N2CCN(C)C3=CC=C1

Formula:

C31H36FN3O4S

Pathway:

GPCR/G Protein,Neuroscience,GPCR/G Protein,Neuroscience

Target:

5-HT Receptor,5-HT Receptor,Dopamine Receptor,Dopamine Receptor