Bioactivity:

VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.

CAS nr:

1809085-30-0

Purity:

98%

Molecular Weight:

387,8

SMILES:

ClC1=CN=C(OCC2=NN([C@H](C)CN(C3=C(F)N=CC=C3)C4=O)C4=C2)C=C1

Formula:

C18H15ClFN5O2

Pathway:

Neuroscience

Target:

GluR