Avasimibe T2753
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
Avasimibe is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 _M) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 _M).
CAS nr:
166518-60-1
Purity:
98%
Molecular Weight:
501,72
SMILES:
CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C
Formula:
C29H43NO4S
Pathway:
Metabolism,Proteases/Proteasome,Metabolism
Target:
Acyltransferase,Acyltransferase,P450
