Bioactivity:

Garcinone D shows significant cytotoxicity against the CEM-SS cell line, with IC(50) value of 3.2 microg/ml; it exhibits dose-dependent enzyme-based microsomal aromatase inhibitory activity. Garcinone D inhibits p65 activation with IC50 values of 3.2 micr

CAS nr:

107390-08-9

Purity:

98%

Molecular Weight:

428,48

SMILES:

CC(C)(O)CCC1=C(OC)C(O)=CC(OC2=CC(O)=C(C/C=C(C)/C)C(O)=C23)=C1C3=O

Formula:

C24H28O7

Pathway:

Metabolism,Immunology/Inflammation,Stem Cells,JAK/STAT signaling,NF-_b,Others

Target:

Reactive Oxygen Species,Reactive Oxygen Species,STAT,STAT,Reactive Oxygen Species,Others