NDI-091143 T7424
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay),indirectly disrupting citrate binding via an unexpected mechanism of inhibition.
CAS nr:
2375840-87-0
Purity:
98%
Molecular Weight:
453,8
SMILES:
COC(=O)c1cc(Cl)c(O)c(S(=O)(=O)Nc2cc(-c3ccccc3)c(F)cc2F)c1
Formula:
C20H14ClF2NO5S
Pathway:
Proteases/Proteasome,Metabolism
Target:
ATP Citrate Lyase,ATP Citrate Lyase
