Bioactivity:

AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).

CAS nr:

942507-42-8

Purity:

98%

Molecular Weight:

451,52

SMILES:

COc1ccc2c(Nc3cc(NC(=O)c4cccc(c4)C(C)(C)C#N)ccc3C)ncnc2c1

Formula:

C27H25N5O2

Pathway:

MAPK,MAPK,Autophagy,Tyrosine Kinase/Adaptors

Target:

Raf,p38 MAPK,Autophagy,c-Fms