Bioactivity:

Zotatifin is a potent and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5�-UTRs (IC50=2 nM). Zotatifin effectively reduces viral infectivity by inhibiting SARS-CoV-2 NP protein b

CAS nr:

2098191-53-6

Purity:

98%

Molecular Weight:

487,55

SMILES:

N#CC1=CC=C([C@@]2(O3)[C@@](C4=C3C=C(OC)N=C4OC)(O)[C@H](O)[C@H](CN(C)C)[C@H]2C5=CC=CC=C5)C=C1

Formula:

C28H29N3O5

Pathway:

Others

Target:

Others