Bioactivity:

Hs-10296 is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.

CAS nr:

1899921-05-1

Purity:

98%

Molecular Weight:

525,66

SMILES:

COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C2CC2)c2ccccc12

Formula:

C30H35N7O2

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

EGFR,EGFR,EGFR