Bioactivity:

Chikusetsusaponin IVa is a novel AMPK activator, can induce insulin secretion from _TC3 cells via GPR4 mediated calcium and PKC pathways, may be developed into a new potential for therapeutic agent used in T2DM patients.

CAS nr:

51415-02-2

Purity:

98%

Molecular Weight:

794,98

SMILES:

C[C@]12CC[C@@H](C([C@@H]1CC[C@@]1([C@@H]2CC=C2[C@]1(CC[C@@]1([C@H]2CC(CC1)(C)C)C(=O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C)(C)C)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)C(=O)O)O)O)O

Formula:

C42H66O14

Pathway:

PI3K/Akt/mTOR signaling

Target:

AMPK