Bioactivity:

SB590885 is an effective B-Raf inhibitor (Ki: 0.16 nM, in a cell-free assay). The selectivity of SB590885 for B-Raf is 11-fold greater over c-Raf, no acts to other human kinases.

CAS nr:

405554-55-4

Purity:

98%

Molecular Weight:

453,54

SMILES:

CN(C)CCOc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc2c(CC\C2=N\O)c1

Formula:

C27H27N5O2

Pathway:

MAPK

Target:

Raf