Bioactivity:

CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 _M.�It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 �M, respectively.CAN508 exhibits a 38-fold selectivity fo

CAS nr:

140651-18-9

Purity:

98%

Molecular Weight:

218,22

SMILES:

OC1=CC=C(/N=N/C2=C(N)NN=C2N)C=C1

Formula:

C9H10N6O

Pathway:

Cell Cycle/Checkpoint

Target:

CDK