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Bioactivity:
RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).
CAS nr:
1416663-77-8
Purity:
98%
Molecular Weight:
518,9
SMILES:
OCC(CO)NC(C(C1=CC(F)=C(F)C=C1)N2C(/C(NC2=O)=C\C(C3=CC=C4Cl)=CNC3=C4C)=O)=O
Formula:
C24H21ClF2N4O5
Pathway:
Apoptosis
Target:
Mdm2