Bioactivity:

CKI-7 free base is a potent and ATP-competitive inhibitor of casein kinase 1 (CK1; IC50: 6 _M; Ki: 8.5 _M) and a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1), and MSK1.

CAS nr:

120615-25-0

Purity:

98%

Molecular Weight:

285,75

SMILES:

O=S(C1=CC=C(Cl)C2=C1C=NC=C2)(NCCN)=O

Formula:

C11H12ClN3O2S

Pathway:

Metabolism,Stem Cells

Target:

Casein Kinase,Casein Kinase