Bioactivity:

GDC-0077 is an orally available and selective inhibitor of PI3K_ (IC50=0.038 nM). GDC-0077 is more selective for mutant versus wild-type PI3K_. GDC-0077 exerts its activity by binding to the ATP binding site of PI3K, thereby inhibiting the phosphorylati

CAS nr:

2060571-02-8

Purity:

98%

Molecular Weight:

407,37

SMILES:

C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1

Formula:

C18H19F2N5O4

Pathway:

PI3K/Akt/mTOR signaling,Apoptosis

Target:

PI3K,Apoptosis