Bioactivity:

ZM 449829 is an effective, selective inhibitor of Janus tyrosine kinase 3 which binds competitively to the JAK3 ATP site (pIC50: 6.8, 5.0, 4.7, and < 5.0 for JAK3, EGFR, JAK1 and CDK4 respectively).

CAS nr:

4452/6/6

Purity:

98%

Molecular Weight:

182,22

SMILES:

O=C(C=C)C1=CC2=C(C=C1)C=CC=C2

Formula:

C13H10O

Pathway:

Others

Target:

Others