Bioactivity:

Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs.

CAS nr:

37905-07-0

Purity:

98%

Molecular Weight:

314,4

SMILES:

CC1=C2[C@H]3O[C@]33CC[C@@H]4C(C)(C)CCC[C@@]4(C)[C@@H]3C=C2OC1=O

Formula:

C20H26O3

Pathway:

PI3K/Akt/mTOR signaling,Stem Cells,JAK/STAT signaling,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling

Target:

mTOR,STAT,STAT,Akt,Akt