Bioactivity:

Manassantin B is a potent inhibitor of NF-�B activation by the suppression of transciptional activity of RelA/p65 subunit of NF-�B. It also possesses anti-EBV lytic replication activity. Manassantin B inhibits interleukin-6-induced signal transducer and

CAS nr:

88497-88-5

Purity:

98%

Molecular Weight:

716,8

SMILES:

COc1ccc(cc1OC)[C@@H](O)[C@@H](C)Oc1ccc(cc1OC)[C@H]1O[C@@H]([C@H](C)[C@H]1C)c1ccc(O[C@H](C)[C@H](O)c2ccc3OCOc3c2)c(OC)c1

Formula:

C41H48O11

Pathway:

Apoptosis,MAPK,Stem Cells,JAK/STAT signaling,NF-_b,Apoptosis,MAPK,Microbiology/Virology,MAPK

Target:

TNF,JNK,STAT,STAT,NF-_B,BCL,p38 MAPK,Antifection,ERK