Bioactivity:

ML 161 is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 _M for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thrombin-induced platelet activation.

CAS nr:

423735-93-7

Purity:

98%

Molecular Weight:

361,23

SMILES:

CCCC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1

Formula:

C17H17BrN2O2

Pathway:

GPCR/G Protein

Target:

Protease-activated Receptor