Bioactivity:

Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and topoisomerase II.

CAS nr:

93908-02-2

Purity:

98%

Molecular Weight:

570,38

SMILES:

O=C(N1)C(C2=C3N([C@@H]([C@@H]([C@@H](O)[C@@H]4OC)O)O[C@@H]4CO)C5=C2C=CC=C5Cl)=C(C(C6=CC=C7)=C3NC6=C7Cl)C1=O

Formula:

C27H21Cl2N3O7

Pathway:

DNA Damage/DNA Repair

Target:

Topoisomerase