Bioactivity:

Lurbinectedin is a DNA minor groove covalent binder. It has an effective anti-tumor activity. Lurbinectedin inhibits RMG1 and RMG2 cell growth (IC50: 1.25 and 1.16 nM, respectively).

CAS nr:

497871-47-3

Purity:

98%

Molecular Weight:

784,87

SMILES:

O[C@@H]([C@@](CC1=CC(C)=C2OC)([H])N(C)[C@]3([H])C1=C2O)N([C@](COC4=O)([H])C5=C(OCO6)C6=C7C)[C@@]3([H])[C@@](SC[C@@]4(NCC8)C9=C8C%10=CC(OC)=CC=C%10N9)([H])C5=C7OC(C)=O

Formula:

C41H44N4O10S

Pathway:

Others

Target:

Others