Bioactivity:

II-B08 is a cell-permeable SHP2 inhibitor (IC50 = 5.5 ﾵM). II-B08 blocks growth factor stimulated ERK1/2 activation and hematopoietic progenitor proliferation.

CAS nr:

1143579-78-5

Purity:

98%

Molecular Weight:

557,61

SMILES:

O=C(C1=CC2=C(N(C)C(C3=CC=CC=C3)=C2C4=CN(CCC(NC5=CC=C(C6=CC=CC=C6)C=C5)=O)N=N4)C=C1O)O

Formula:

C33H27N5O4

Pathway:

Target: