Bioactivity:

BI-4924 is an inhibitor of phosphoglycerate dehydrogenase (PHGDH) (IC50=3 nM). It has excellent Microsomal and hepatocytic stability. Intracellular trapping of BI-4924 disrupts serine biosynthesis at 72 h ( IC50: 2200 nM).

CAS nr:

2244452-09-1

Purity:

98%

Molecular Weight:

499,36

SMILES:

O=C(O)CS(=O)(C1=CC=C([C@H](NC(C(N2C)=CC3=C2C=C(C)C(Cl)=C3Cl)=O)CO)C=C1)=O

Formula:

C21H20Cl2N2O6S

Pathway:

Others

Target:

Others