Bioactivity:

KDM5-C70 is an ethyl ester derivative of KDM5-C49. KDM5-C70 is an effective, cell-permeable, and pan-KDM5 histone demethylase inhibitor. KDM5-C70 has an antiproliferative effect in myeloma cells, inducing a genome-wide elevation of H3K4me3 levels.

CAS nr:

1596348-32-1

Purity:

98%

Molecular Weight:

336,43

SMILES:

O=C(OCC)C1=CC=NC(CNCC(N(CCN(C)C)CC)=O)=C1

Formula:

C17H28N4O3

Pathway:

Chromatin/Epigenetic

Target:

Histone Demethylase