Bioactivity:

Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms, respectively).

CAS nr:

152-53-4

Purity:

98%

Molecular Weight:

288,18

SMILES:

Cl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1

Formula:

C11H14ClN5.ClH

Pathway:

Metabolism,Microbiology/Virology

Target:

Drug Metabolite,Parasite