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Bioactivity:
ON 146040 is a potent inhibitor of PI3K_ and PI3K_ (IC50�14 and 20 nM, respectively) .
CAS nr:
1404231-34-0
Purity:
98%
Molecular Weight:
489,55
SMILES:
CN(CC1)CCN1C(C=C2)=CC=C2NC3=NC(S/C(C(N4)=O)=C\C5=CC=C([N+]([O-])=O)C=C5)=C4C=N3
Formula:
C24H23N7O3S
Pathway:
PI3K/Akt/mTOR signaling
Target:
PI3K