Bioactivity:

Highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks _-MSH- and MTII-induced hypotension and bradycardia in rats, f

CAS nr:

212370-59-7

Purity:

98%

Molecular Weight:

1266,5

SMILES:

CCCC[C@@H]1NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccc3ccccc3c2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)[C@H](CCCNC(N)=N)NC1=O)C(N)=O)NC(C)=O

Formula:

C58H79N19O10S2

Pathway:

GPCR/G Protein,Neuroscience

Target:

Melanocortin Receptor,Melanocortin Receptor