Bioactivity:

ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.

CAS nr:

2055597-12-9

Purity:

98%

Molecular Weight:

473,93

SMILES:

O=C(C1=CN(C2=NC(NC3CCOCC3)=NC=C2C)C=N1)N[C@@H](C4=CC(F)=CC(Cl)=C4)CN

Formula:

C22H25ClFN7O2

Pathway:

MAPK

Target:

ERK