Bioactivity:

SB 297006 is an antagonist of C-C chemokine receptor 3 (CCR3; IC50 = 39 nM), which normally is activated by eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES, and MIP-1_. It is at least 250-fold selective for CCR3 over a panel of other chemokine receptors. SB 2970

CAS nr:

58816-69-6

Purity:

98%

Molecular Weight:

342,4

SMILES:

O=[N+]([O-])c2ccc(C[C@H](NC(=O)c1ccccc1)C(=O)OCC)cc2

Formula:

C18H18N2O5

Pathway:

Microbiology/Virology,Immunology/Inflammation

Target:

CCR,CCR