Bioactivity:

1. Atractylenolide II has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.

CAS nr:

73069-14-4

Purity:

98%

Molecular Weight:

232,32

SMILES:

CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C[C@@H]2OC1=O

Formula:

C15H20O2

Pathway:

Stem Cells,JAK/STAT signaling,MAPK,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Apoptosis,MAPK

Target:

STAT,STAT,p38 MAPK,Akt,Akt,Apoptosis,ERK