Bioactivity:

Picropodophyllin (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as recept

CAS nr:

477-47-4

Purity:

98%

Molecular Weight:

414,41

SMILES:

COc1cc(cc(OC)c1OC)[C@H]1[C@H]2[C@H](COC2=O)[C@@H](O)c2cc3OCOc3cc12

Formula:

C22H22O8

Pathway:

Tyrosine Kinase/Adaptors,Apoptosis

Target:

IGF-1R,Apoptosis