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Bioactivity:
TAS4464 is a highly potent and selective inhibitor of the NEDD8 activating enzyme (IC50: 0.955 nM).
CAS nr:
1848959-10-3
Purity:
98%
Molecular Weight:
506,51
SMILES:
NC1=NC=NC2=C1C(C#CC3=C(F)C=CC=C3OCC)=CN2[C@@H]4O[C@H](CNS(=O)(N)=O)[C@@H](O)[C@H]4O
Formula:
C21H23FN6O6S
Pathway:
Ubiquitination
Target:
E1/E2/E3 Enzyme