Bioactivity:

ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, ADT-OH markedly attenuated tPA-enhanced Akt activation and VEGF expression in brain microvascular e

CAS nr:

18274-81-2

Purity:

98%

Molecular Weight:

226,33

SMILES:

Oc1ccc(cc1)-c1cc(=S)ss1

Formula:

C9H6OS3

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling

Target:

VEGFR,VEGFR,Akt,Akt