Bioactivity:

GW274150 shows less potency for both humans or rats endothelial NOS (eNOS) and neuronal NOS (nNOS). GW274150 is a selective and NADPH-dependent inhibitor of human inducible nitric oxide synthase (iNOS) (IC50=2.19 _M; Kd=40 nM) and rat iNOS (ED50=1.15 _M).

CAS nr:

210354-22-6

Purity:

98%

Molecular Weight:

219,3

SMILES:

N[C@@H](CCSCCNC(C)=N)C(O)=O

Formula:

C8H17N3O2S

Pathway:

Immunology/Inflammation

Target:

NOS