Bioactivity:

TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGR_, and PDFGR_, respectively).

CAS nr:

1005780-62-0

Purity:

98%

Molecular Weight:

445,47

SMILES:

O=C(C1=CC(C)=NN1C)NC2=CC(OC3=NN4C(C=C3)=NC(NC(C5CC5)=O)=C4)=CC=C2C

Formula:

C23H23N7O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis

Target:

PDGFR,PDGFR,VEGFR,VEGFR