Bioactivity:

NEU-1045 is a T. brucei proliferation inhibitor, and is a promising lead with cross-pathogen activity. NEU-1045 inhibited T. brucei, T. cruzi, and L. major proliferation with good potency (T. brucei EC50 = 0.37 _M; T. cruzi EC50 = 2.8 _M; L. major EC50 =

CAS nr:

T28161

Purity:

98%

Molecular Weight:

569,65

SMILES:

FC1=CC(COC(C=C2)=CC=C2NC3=CC=NC(C3=C4)=CC=C4C5=CC=C(S(N6CCOCC6)(=O)=O)C=C5)=CC=C1

Formula:

C32H28FN3O4S

Pathway:

Target: