Bioactivity:

Ribociclib succinate is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It also is over 1,000-fold less potent against the cyclin B/CDK1 complex.

CAS nr:

1374639-75-4

Purity:

98%

Molecular Weight:

552,63

SMILES:

OC(=O)CCC(O)=O.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1

Formula:

C27H36N8O5

Pathway:

Cell Cycle/Checkpoint

Target:

CDK