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TargetMol Chemicals

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TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

www.targetmol.com

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Avagacestat T6249

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Specifications

1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Avagacestat (BMS-708163) is a potent, selective, orally bioavailable _-secretase inhibitor of A_40 and A_42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.

CAS nr:

1146699-66-2

Purity:

98%

Molecular Weight:

520,88

SMILES:

NC(=O)[C@@H](CCC(F)(F)F)N(CC1=C(F)C=C(C=C1)C1=NOC=N1)S(=O)(=O)C1=CC=C(Cl)C=C1

Formula:

C20H17ClF4N4O4S

Pathway:

Proteases/Proteasome,Neuroscience,Stem Cells

Target:

Gamma-secretase,Gamma-secretase,Gamma-secretase