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Bioactivity:
SEL120-34A is a selective, orally available, and ATP-competitive CDK8 inhibitor (IC50s: 4.4 nM and 10.4 nM for CDK8/CycC and CDK19/CycC) with antitumor activity.
CAS nr:
1609522-33-9
Purity:
98%
Molecular Weight:
414,14
SMILES:
CC1=C2C3=C(C(Br)=C1Br)CCCN3C(N4CCNCC4)=N2
Formula:
C15H18Br2N4
Pathway:
Cell Cycle/Checkpoint
Target:
CDK