Bioactivity:

S39625, an E-ring camptothecin keto analogue, is a stable, potent, and selective topoisomerase I inhibitor without being substrates of drug efflux transporters. Nanomolar concentrations of S39625 induces intense and persistent histone gamma-H2AX. The chem

CAS nr:

536711-20-3

Purity:

98%

Molecular Weight:

430,46

SMILES:

O=C(C1)[C@](O)(CC)C2=C1C(N3CC4=C(C5CCC5)C6=CC(OCO7)=C7C=C6N=C4C3=C2)=O

Formula:

C25H22N2O5

Pathway:

Target: