Bioactivity:

Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than finasteride (IC50 = 0.38 +/- 0.06 mic

CAS nr:

13018-10-5

Purity:

98%

Molecular Weight:

376,5

SMILES:

C\C=C(\C)C(=O)O[C@@H]1C[C@H](C)[C@H]2CC(=O)C(C)=C2C[C@@H]1C(C)(C)OC(C)=O

Formula:

C22H32O5

Pathway:

MAPK,MAPK,Proteases/Proteasome,NF-_b,NF-_b,MAPK,Proteases/Proteasome,Cell Cycle/Checkpoint,DNA Damage/DNA Repair

Target:

ERK,JNK,MMP,NF-_B,I_B/IKK,p38 MAPK,Tyrosinase,DNA/RNA Synthesis,DNA/RNA Synthesis