Clonality:

Polyclonal

Alternative names:

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Species reactivity:

Human,Mouse,Rat,Chicken,Dog,Cow,

Host species:

Rabbit

Concentration:

1mg/ml

Applications:

IF=1:50-200

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