Anti-CD79b Reference Antibody (polatuzumab vedotin-piiq) CHB256
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Specifications
| 100 μg / 1 mg |
Description:
Polatuzumab vedotin (Polivy) is an ADC consisting of a CD79b-directed antibody and Monomethyl auristatin E (MMAE) that can be used in combination with bendamustine and rituximab for the treatment of adult patients with at least two relapses or refractory diffuse large B-cell lymphoma. Polatuzumab vedotin binds to CD79b and is internalized by tumor cells. MMAE is cleaved from cells by lysosomal protease and promotes tumor cell apoptosis by inhibiting microtubule formation.
Product type:
Antibody
Host:
CHO
Target name:
CD79b
Target species:
Human
Isotype:
IgG
Buffer:
100 mM Pro-Ac 20 mM Arg pH5.0
Applications:
ELISA、FACS、Kinetics (BLI)、Kinetics (SPR)、Functional assay
More info:
Email: info@sobekbio.com
Orders:
Email: orders@sobekbio.com