PIN1 inhibitor API-1 M24694
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Specifications
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CAS Number:
680622-70-2
Target:
Other Targets
Molecular formula:
C15H13F3N6O2
Formula weight:
366,3
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
PIN1 inhibitor API-1 is a specific Pin1 inhibitor (IC50: 72.3 nM). PIN1 inhibitor API-1 retains the active conformation of pXPO5 and restores the ability of pXPO5 to transport pre-miRNAs from the nucleus to cytoplasm, thus up-regulating the anticancer miRNA biogenesis to suppress both in vitro and in vivo hepatocellular carcinoma development.
Note:
Research use only, not for human use.
More info:
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