PD146176 M24370
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Specifications
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CAS Number:
4079-26-9
Target:
Autophagy
Molecular formula:
C15H11NS
Formula weight:
237,32
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
PD146176 is an inhibitor of 15-Lipoxygenase (15-LO) , it inhibits rabbit reticulocyte 15-LO with Ki of 197 nM and IC50 of 0.54 μM. PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
Note:
Research use only, not for human use.
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