N-Acetyl-Ser-Asp-Lys-Pro M22966

CAS Number:

127103-11-1

Target:

RAAS

Molecular formula:

C20H33N5O9

Formula weight:

487,5

Purity:

>98% (HPLC)

Stability:

≥ 2 years

Product description:

Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethality in mice.N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP) is a specific substrate for the N-terminal site of ACE and increases 5-fold during ACE inhibitor therapy.  AcSDKP inhibited the proliferation of isolated cardiac fibroblasts (P<0.05) but significantly stimulated the proliferation of vascular smooth muscle cells. 

Note:

Research use only, not for human use.

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