Gap19 acetate(1507930-57-5,free) M22965
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Specifications
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CAS Number:
1507930-57-5
Target:
Other Targets
Molecular formula:
C55H96N14O13
Formula weight:
1161,44
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.Hemichannel inhibition is due to the binding of Gap19 to the C-terminus (CT) thereby preventing intramolecular CT-CL interactions. The peptide inhibited Cx43 hemichannel unitary currents in both HeLa cells exogenously expressing Cx43 and acutely isolated pig ventricular cardiomyocytes.
Note:
Research use only, not for human use.
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