TMN355 M22935
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Specifications
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CAS Number:
1186372-20-2
Target:
Other Targets
Molecular formula:
C21H14ClFN2O2
Formula weight:
380,8
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
TMN355 is a potent chemical inhibitor of cyclophilin A and reduces foam cell formation and cytokine secretion,and is used for atherosclerosis. Silencing cyclophilin A in THP-1 cells and human monocytes using siRNA or chemical inhibitor, TMN355 resulted in decrease in lipid uptake by 65-75% even after exposure to oxidized LDL.
Note:
Research use only, not for human use.
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