Resatorvid M22910
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Specifications
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CAS Number:
243984-11-4
Target:
TLR
Molecular formula:
C15H17ClFNO4S
Formula weight:
361,82
Purity:
>98% (HPLC)
Stability:
≥ 2 years
Product description:
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid inhibits IL-6, TNF-R and NO production (IC50s: 1.3 nM, 1.9 nM, and 1.8 nM).Resatorvid suppresses the production of NO, TNF-α, and IL-6 from LPS-stimulated human peripheral blood mononuclear cells (PBMCs, IC50s: 11-33 nM).
Note:
Research use only, not for human use.
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